Home

• 1 Introduction
• 1.1 The use of statistics in research
• 1.2 Presenting medical statistics
• 1.3 This book
• 1.4 Final words
• 2 Introduction to the research process
• 2.1 Defining the research question
• 2.2 Writing a research protocol
• 2.3 Data collection
• 2.4 Transferring the data to computer
• 2.5 Data checking and cleaning
• 2.6 Using computer packages
• 2.7 Record keeping
• 2.8 Presenting results
• 2.9 When to seek help from a statistician
• 3 Writing a research protocol
• 3.1 The development cycle
• 3.2 Title
• 3.3 Aims of the research study
• 3.4 Primary and secondary aims
• 3.5 Study design
• 3.6 Sample size calculations
• 3.7 Plan of statistical analysis
• 3.8 Required approval for research
• 3.9 When applications fail
• 4 Writing up a research study
• 4.1 Introduction
• 4.2 Contents of each section of the report
• 4.3 Special circumstances
• 5 Introduction to presenting statistical analyses
• 5.1 Introduction
• 5.2 Presenting numerical data
• 5.3 Beginning the results section
• 5.4 Describing the results of the recruitment process
• 5.5 Assessing non-response bias
• 5.6 Presenting the results for different media
• 5.7 Drawing up a profile of a group of subjects
• 5.8 Drawing graphs
• 5.9 Using text to refer to tables and graphs
• 5.10 Presenting categorical data
• 5.11 Presenting continuous data
• 6 Single group studies
• 6.1 Introduction
• 6.2 Prevalence studies
• 6.3 Presenting the results of prevalence studies
• 6.4 Screening and diagnostic studies: Sensitivity and specificity
• 6.5 Presentation of sensitivity and specificity
• 6.6 Comment on results
• 6.7 Screening studies for rare conditions
• 6.8 Extensions to sensitivity and specificity
• 7 Comparing two groups
• 7.1 Introduction
• 7.2 Graphical presentation of continuous unpaired data
• 7.3 Continuous unpaired data: The two-sample t test
• 7.4 Mann–Whitney U test
• 7.5 Comparing two proportions
• 8 Analysing matched or paired data
• 8.1 Introduction
• 8.2 Continuous paired data: The paired t test
• 8.3 Non- Normal data
• 8.4 Matched case- control data
• 8.5 Matched cohort data
• 9 Analysing relationships between variables
• 9.1 Introduction
• 9.2 Correlation
• 9.3 Regression
• 10 Multifactorial analyses
• 10.1 Introduction
• 10.2 One-way analysis of variance
• 10.3 Multiple regression
• 10.4 Logistic regression
• 11 Survival analysis
• 11.1 Introduction
• 11.2 Kaplan–Meier estimates of survival rates
• 11.3 The logrank test
• 11.4 Cox regression
• 12 Presenting a randomized controlled trial
• 12.1 Introduction to the CONSORT statement
• 12.2 The CONSORT checklist
• 12.3 Intention-to-treat analysis
• 12.4 Cluster randomized trials
• 12.5 Reporting guidelines for other study designs
• 13 Presenting a meta- analysis
• 13.1 Introduction to systematic reviews and meta-analysis
• 13.2 Statistics and meta-analysis
• 13.3 The PRISMA statement
• 13.4 Reviewing meta-analyses