Table of Contents
- 1 Introduction
- 1.1 The use of statistics in research
- 1.2 Presenting medical statistics
- 1.3 This book
- 1.4 Final words
- 2 Introduction to the research process
- 2.1 Defining the research question
- 2.2 Writing a research protocol
- 2.3 Data collection
- 2.4 Transferring the data to computer
- 2.5 Data checking and cleaning
- 2.6 Using computer packages
- 2.7 Record keeping
- 2.8 Presenting results
- 2.9 When to seek help from a statistician
- 3 Writing a research protocol
- 3.1 The development cycle
- 3.2 Title
- 3.3 Aims of the research study
- 3.4 Primary and secondary aims
- 3.5 Study design
- 3.6 Sample size calculations
- 3.7 Plan of statistical analysis
- 3.8 Required approval for research
- 3.9 When applications fail
- 4 Writing up a research study
- 4.1 Introduction
- 4.2 Contents of each section of the report
- 4.3 Special circumstances
- 5 Introduction to presenting statistical analyses
- 5.1 Introduction
- 5.2 Presenting numerical data
- 5.3 Beginning the results section
- 5.4 Describing the results of the recruitment process
- 5.5 Assessing non-response bias
- 5.6 Presenting the results for different media
- 5.7 Drawing up a profile of a group of subjects
- 5.8 Drawing graphs
- 5.9 Using text to refer to tables and graphs
- 5.10 Presenting categorical data
- 5.11 Presenting continuous data
- 6 Single group studies
- 6.1 Introduction
- 6.2 Prevalence studies
- 6.3 Presenting the results of prevalence studies
- 6.4 Screening and diagnostic studies: Sensitivity and specificity
- 6.5 Presentation of sensitivity and specificity
- 6.6 Comment on results
- 6.7 Screening studies for rare conditions
- 6.8 Extensions to sensitivity and specificity
- 6.9 Further reading
- 7 Comparing two groups
- 7.1 Introduction
- 7.2 Graphical presentation of continuous unpaired data
- 7.3 Continuous unpaired data: The two-sample t test
- 7.4 Mann–Whitney U test
- 7.5 Comparing two proportions
- 7.6 Further reading
- 8 Analysing matched or paired data
- 8.1 Introduction
- 8.2 Continuous paired data: The paired t test
- 8.3 Non- Normal data
- 8.4 Matched case- control data
- 8.5 Matched cohort data
- 8.6 Further reading
- 9 Analysing relationships between variables
- 9.1 Introduction
- 9.2 Correlation
- 9.3 Regression
- 9.4 Further reading
- 10 Multifactorial analyses
- 10.1 Introduction
- 10.2 One-way analysis of variance
- 10.3 Multiple regression
- 10.4 Logistic regression
- 11 Survival analysis
- 11.1 Introduction
- 11.2 Kaplan–Meier estimates of survival rates
- 11.3 The logrank test
- 11.4 Cox regression
- 11.5 Further reading
- 12 Presenting a randomized controlled trial
- 12.1 Introduction to the CONSORT statement
- 12.2 The CONSORT checklist
- 12.3 Intention-to-treat analysis
- 12.4 Cluster randomized trials
- 12.5 Reporting guidelines for other study designs
- 13 Presenting a meta- analysis
- 13.1 Introduction to systematic reviews and meta-analysis
- 13.2 Statistics and meta-analysis
- 13.3 The PRISMA statement
- 13.4 Reviewing meta-analyses
- 13.5 Further reading
- References
- Index